PE標(biāo)記的胰島素樣生長(zhǎng)因子1受體抗體

Name: PE標(biāo)記的胰島素樣生長(zhǎng)因子1受體抗體bs-4985R-PE
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簡(jiǎn)要描述：This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin